tag:blogger.com,1999:blog-9076190155284676524.post4108077729616816840..comments2024-03-28T18:51:35.450-04:00Comments on Your Diabetes May Vary: From the News Wire: Lantus vs NPH: Safer not better controlUnknownnoreply@blogger.comBlogger1125tag:blogger.com,1999:blog-9076190155284676524.post-10173636118778300802008-07-18T13:59:00.000-04:002008-07-18T13:59:00.000-04:00Interestingly, the standard of using NPH as the co...Interestingly, the standard of using NPH as the control misses the fact that the Lente series (consisting of Semilente, Lente and Ultralente) was widely-regarded as superior in terms of phamcokinetics/pharmacodynamics (PK/PD), yet because it is more difficult to make, it was among the first range of older products to be removed from the market. However, a better review might compare Lantus/Levemir to Lente products (still sold in a number of other countries) to see if there is any difference in the incidence of hypoglycemia -- I would bet that analogues would not show much of statistical difference reducing severe hypoglycemic episodes if they compared it to Lente.<BR/><BR/>See <A HREF="http://www.hbns.org/getDocument.cfm?documentID=1741" REL="nofollow">http://www.hbns.org/getDocument.cfm?documentID=1741</A> for more.Scott Shttps://www.blogger.com/profile/03286529314567223617noreply@blogger.com