October 15, 2008

From The News Wire: Misc News starting with More on Mice.

OK News hounds here are a few quickes to look at.

Protein Made In Liver Restores Blood Glucose In Type 1 Diabetes (Mouse) Model


ScienceDaily (Oct. 15, 2008) — A protein made by the liver in response to inflammation and used to treat patients suffering from a genetic form of emphysema has been shown to restore blood glucose levels in a mouse model of Type 1 diabetes mellitus, according to a new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC)....

"To cure Type 1 diabetes, it will not be enough to halt the destructive T-cell-dependent autoimmune attack on beta cells," explains the study's lead author Maria Koulmanda, PhD, Director of Non-Human Primate Research in the Transplant Center at Beth Israel Deaconess Medical Center (BIDMC) and Associate Professor of Surgery at Harvard Medical School (HMS). "We think that it will also be necessary to restore proper insulin signaling, and the way to do that is by eliminating the curious inflammatory state that exists in muscle, fat and other insulin-sensitive tissues."
OK, unless the destructive T-cells are stopped nothing is going to work. (Hence all the interest in Faustman’s work.) That is the point of this little story in US News & World Report:

Beyond Insulin: Searching for a Cure to Type 1 Diabetes

And finally:

Positive Results Seen in Juvenile Diabetes Vaccine Study