January 21, 2013

Josh's January Update on T1D Cure Research

Regular YDMV readers know I am a big fan and cheerleader for Josh Levy's site http://cureresearch4type1diabetes.blogspot.com. I like that someone smarter than me reads all these studies and like even more the reviews and discussions.

His January 2013 update is here: http://cureresearch4type1diabetes.blogspot.com/2013/01/possible-cures-for-type-1-in-news.html

Topics covered in detail include:
Kamada Alpha-1 Antitrypsin (AAT). 
This study is important for a couple of reasons.  First, because of the number of AAT clinical trials. I know of a five AAT clinical trials aimed at type-1 diabetes going on now.  That's a lot; more than any other single drug.
LCT Updates  
LCT is developing an encapsulated pig beta cell cure for type-1 diabetes. The coating allows blood sugar in, and insulin out, but does not allow the body's immune system to attack the beta cells. It also allows nutrients in and waste products out. This allows the beta cells to naturally grow and to react to the body's sugar by generating insulin which goes into the body's blood system. 
Update from Scott King on Islet Sheet Project 
An Islet Sheet is a specific beta cell encapsulation technique, similar to what LCT is trying to do.  Because Islet Sheets have not yet started human trials, I don't follow this research very closely.  However, I know others are very interested in it, and Scott King posted an update on his blog, which you can read here:http://www.hanumanmedicalfoundation.org/blog/2012/11/26/signal-breakthrough-islet-sheets-thrive-in-pig/ 

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