February 28, 2008

Another way of (Mis?) Understanding Diabetes

The financial industry version.

The Motley fool published an article putting Biodel in with 4 other “deathbed stocks.” In part they say, “Biodel's VIAject system will compete against Humulin, made by Eli Lilly. However, although it seems to be absorbed more quickly than Humulin, there's nothing yet to suggest that will be enough to cause patients to switch.” They also noted that oral insulin took a hit with “the bong.” [link]

Funny it was exactly the faster absorption that got me interested in the company and a bought a few shares for kicks. Faster injected insulin strikes me as much more interesting than oral insulin.

Meanwhile JP Morgan started coverage of the Same Biodel with and “Overweight” rating saying, “VIAject's potential superior clinical profile could compete with the current products of Eli Lilly and Co and Novo Nordisk that are dominating the market, and could capture 10 to 15 percent of the market by 2012, JP Morgan said in a note to clients.”

So apparently even in the financial markets YDMV.

So my fellow T1 people what do you think is a faster insulin something you would buy?

February 23, 2008

Diabetes.org Back

The main site is back but the forums are still MIA.

diabetes.org expired

Diabetes.org is down. Apparently they didn't bother to renew their domain name registration.

"diabetes.org
expired on 02/17/2008 and is pending renewal or deletion."

Smooth move.

Newbie Advice III – Why aren’t we in The Caymans?

If it is a ‘Honeymoon’ why aren’t we at a beach in on some nice Island?

Newbie Tip I was about diabetes mind games and II was a vocabulary lesson. We are getting brave here and we are going to mix mind games and vocabulary. Keep you arms and legs inside the ride at all times. We are going to talk about the term ‘Honeymoon.’

We are going to go with sarcasm here. You’re new to diabetes and a little dark humor should help with the stress.

As far as I can tell the phrase ‘Honeymoon’ as relating to diabetes was coined by a sadist.
The dude’s marriage must have really been god awful if he thought it was a good analogy to compare diabetes care with the first blush of marital bliss. Maybe it wasn’t a guy but I am not convinced that would explain it either.

Just to be sure I wasn’t nuts I looked up the word honeymoon:
1) a vacation or trip taken by a newly married couple
2) the month or so following a marriage
3) any period of blissful harmony
4) any new relationship characterized by an initial period of harmony and goodwill

None of those come close to fitting the diabetes situation. Some confuse thing even more.

Let start with the first one: Diabetes isn’t a vacation, it is forever. You can’t take a break for week or two from it and comeback and pick up where you left off without issues. And unlike a new marriage there is no pre-nup, no divorce option - you’re stuck with it - For Life.

Two: The month thing just screws people up. The diabetes ‘Honeymoon’ isn’t a few weeks to a month but insulin resistance is. See Newbie Tip I.

The ‘Honeymoon is the period from diagnosis to the point that all practical insulin production in the pancreas is gone. It takes a while, a year to years is as good a time frame to think about as any - Your Diabetes May Vary. From our experience insulin production goes out in fits and spurts.

Blissful: If you think there is anything “Blissful” about diabetes you are on crack. As for the ‘Honeymoon’ well insulin production goes out in fits and spurts typically just when you think you have a handle on managing blood sugar. Diabetes is real good at changing just when you think you getting the hang of dealing with it. It is a mind game and growth Spurts and puberty just ad to the ‘Bliss’ of diabetes management making the ‘Honeymoon’ oh so much sweeter!

Ok it doesn’t make it sweeter. But you learn to manage and that the whole point.

As for harmony and goodwill I can’t see it, must folks new relationship with diabetes is all about stress and confusion. ‘Honeymoon’ my eye. About the only thing I can say is similar between the ‘Honeymoon’ and a honeymoon in the traditional idea, is that they both eventually end.

The ‘Honeymoon’ last longer than 1, 2 and 4. Best wished that you have a marriage like 3.

The ‘Honeymoon’ ends when the body stops insulin production. You are there when the average Total Daily Dose if insulin is about 1 unit per kilo of weight (2.2 lbs for us Americans who don’t do the metric system.)

Now just because the ‘Honeymoon’ is over don’t get all excited and think your diabetes will be easy to manage. Growth, puberty, exercise, stress, excitement, weather, fat, grease alcohol, pizza and a whole lot more screw up the best made diabetes plans.

February 22, 2008

Climb Every Mountain

Cue the Van Trapp singers. This dude is type 1 and does all kinds of cool stuff like climbing mountains, including Everest.

I think he is probably a better type 1 role model than that Rock of Love clown from Poison.

http://www.scrippsnews.com/node/30872
http://www.willcrossmotivates.com/index.html

February 21, 2008

From The News Wire: Stem cells make insulin

Human stem cells were made into insulin producing cells in... mice.

If I had a dollar for every one of these cure in mice stories I could afford a CGM....

Stem Cell Therapy Controls Diabetes in Mice

February 17, 2008

From The News Wire: Kiss a Pig

This one is fun. Fund raises compete to kiss a pig. Apparently the high money raises get to kiss the pig not the low being forced.


February 15, 2008

National Treasure

JDRF sent us an invitation to join them for a bus trip to visit Congress as part of "Government Day 2008." I am a history geek. I take my bill of rights seriously. I also am a big fan of the combo meal. So how could I resist the 1st Amendment Special: peaceably assemble with a side order of petition the government?

The weather forecast was ominous but Delaney and I played hooky from our respective responsibilities anyway. We met the bus at a local Mall and were off with a dozen other families to DC.

Kimball and Conner were going to come too. In large part we hoping to see an old friend of Kim’s Dad who works in the Capitol. But by the day of the trip Pop Pop hadn’t been able to connect with his Pal and Kimball decided to skip the trip and go to biology class.

Yes Bio - She was inspired at last years Children With Diabetes conference to return to school seeking a nursing degree. It has been a while since she was last in college and she is bringing her science classes up to date. She is doing great by working hard - she decided not to play hooky. Connor has a lead part in a school play. It was a big rehearsal day. That left Delaney and I on the bus.

A few of our group went off to see their Congressman just as we arrived. The rest of us, not being special, caught lunch before our appointed rounds. Lunch was revealing. There and through out the day it was clear just how many Americans come to exercise their right to petition the government. There were Purple Heart Veterans, Mental Health Groups, Native Americans, Vision Impaired groups with their working dogs, of course Juvenile Diabetics and assorted alphabet soup groups (Usually starting or ending with an “A.” Probably one was "AAAAAAA" - American Association of Assorted American in Alphabetic Acronym Associations.)

I got a strong impression that this was what life at “Court” has been like for centuries, from Chinese Dynasties, Romans, Kings, Parliaments, Assemblies East and West. A lot of people twisting their cap in their hands and a lot of officials trying to get work done but realizing that seeing all these people is part of their work.

If you haven’t been, The US Congress buildings are less the Halls of Power than the Maze of Passageways with lots of security people. Delaney was impressed that all the police were so nice. That’s cool. A lot of someones deserve a compliment for that, consistent good service never happens by accident.

I found it funny that the kids were all a buzz with talk that Nicholas Cage was in this or that stairway in a scene in National Treasure. Nick is apparently why DC is special.

At some point we got a call from Pop Pop’s that his friend called back and would be there after all. We could see him around 3:00 if we wanted. Delaney and I broke way from the JDRF group and found our way, with the help of the very nice capitol security people to, his office.

He was gracious and warm. Her told Delaney how her grand parents we two of seven people knocking on doors in his first campaign years ago. He spoke about his grand daughter and that helped Delaney feel comfortable enough to answer questions about her day, her pump and diabetes. Delaney gave him one of our Love Ya / Mean It walk pins. After a pleasant visit we left the Majority Leader's office and Capitol Building.

We met the rest of the group at the bus. The weather was, as expected, bad. “Wintery Mix” and the DC Rush Hour - Yahoo! It was clear the trip was going to take a lot longer than expected. I had some juice boxes hidden in case one of the kids went hypo. It was going to be a long night an all the snacks were going to disappear always have something for a low handy. The bus driver did a great job. The kids had a ball playing in the bus and they didn't much care it took a long time.

We met a lot of very nice people; other type 1 families, capitol police, congressional aides, a members of Congress, lots of folks visiting with their government, the Majority Leader of the U.S. House of Representatives and a darn good bus driver.

There was a primary election that day in DC and the surrounding states. (Some polls stayed open late due to the weather.) I found it particularly wonderfully that we and many others peacefully assembled and petitioned our collective government while the future political makeup of that Government was being determined at the polls and the Police impressed a little girl with how polite they were.

Who needs Nick cage, our Constitution working is the National Treasure.

February 7, 2008

Diabetech in the News

Our friend Kevin McMahon's company is in the news. Kevin is a thoughtful guy who has added comments here at YDMV and even more at CWD. Check out his news:

Following several years of research and development in over a dozen clinical trials, Diabetech is pleased to launch the GlucoMON-RT subscription service available immediately to the broad diabetes community. At $29.95/mo, Diabetech has solved not only the problem of keeping people with diabetes safe (ie - children with type 1 safe at school) with a real-time remote monitoring solution but also making it affordable to millions of people in the US and soon expanding to other parts of the globe

http://www.prweb.com/releases/2008/2/prweb678523.htm


Congratulations Kevin & Co. Best Wishes

Bequest to JDRF

From the news wire a number of good stories about support for JDRF.

I knew I liked bratts, - Johnsonville members' contribution, the walk raised $125,000. The money raised will fund research to find a cure for Type 1 (juvenile) diabetes.

http://www.sheboygan-press.com/apps/pbcs.dll/article?AID=/20080206/SHE04/802060328/1097/SHElife

That is great but all there is to say about this one is WOW!

http://www.washingtonpost.com/wp-dyn/content/article/2008/02/06/AR2008020604252.html?hpid=moreheadlines